发明公开
EP3233843A1 ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS
审中-公开
ISOXAZOLE HYDROXAMIC酸化合物作为LPXC抑制剂
- 专利标题: ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS
- 专利标题(中): ISOXAZOLE HYDROXAMIC酸化合物作为LPXC抑制剂
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申请号: EP15816893.0申请日: 2015-12-15
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公开(公告)号: EP3233843A1公开(公告)日: 2017-10-25
- 发明人: FU, Jiping , JIN, Xianming , KARUR, Subramanian , LAPOINTE, Guillaume , MADERA, Ann Marie , SWEENEY, Zachary Kevin
- 申请人: Novartis AG
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Marti, Christiane
- 优先权: US201462092402P 20141216
- 国际公布: WO2016097995 20160623
- 主分类号: C07D413/06
- IPC分类号: C07D413/06 ; A61K31/42 ; C07D413/12 ; C07D261/08
摘要:
This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for treating infections caused by Gram-negative bacteria.
公开/授权文献
- EP3233843B1 ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS 公开/授权日:2019-10-16
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