发明公开
- 专利标题: PROPHYLAXIS OF THROMBOSIS
- 专利标题(中): 预防血栓形成
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申请号: EP15874231.2申请日: 2015-12-21
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公开(公告)号: EP3237007A1公开(公告)日: 2017-11-01
- 发明人: REED, Guy L.
- 申请人: Translational Sciences Inc.
- 申请人地址: 1840 Overton Park Avenue Memphis, TN 38122 US
- 专利权人: Translational Sciences Inc.
- 当前专利权人: Translational Sciences Inc.
- 当前专利权人地址: 1840 Overton Park Avenue Memphis, TN 38122 US
- 代理机构: Heinonen & Co
- 优先权: US201462095462P 20141222
- 国际公布: WO2016106186 20160630
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/38 ; A61P9/10
摘要:
The invention provides a method and composition for preventing thrombosis and complications associated therewith by targeting Sf2 directly. The invention provides Sf2-deficiency or prophylactic administration of a therapeutic agent, such as a Sf2 antagonist or a Sf2 antibody, markedly reduces thrombus formation that would otherwise be caused due to surgery, immobility, genetic abnormality, cancer, trauma, or other risk factors.
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