发明公开
- 专利标题： TERTIARY ALCOHOL IMIDAZOPYRAZINE BTK INHIBITORS
- 专利标题（中）： 第三醇：咪唑并吡嗪BTK抑制剂
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申请号： EP15875974.6申请日： 2015-12-17
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公开(公告)号： EP3240546A1公开(公告)日： 2017-11-08
- 发明人: LIU, Jian , KOZLOWSKI, Joseph, A. , ANDRESEN, Brian, M , BOGA, Sobhana Babu , GAO, Xiaolei , GUIADEEN, Deodialsingh , CAI, Jiaqiang , WANG, Dahai , WU, Hao , YANG, Chundao
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Jaap, David Robert
- 优先权： PCT/CN2014/095764 20141231
- 国际公布： WO2016109222 20160707
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/55 ; C07D487/04 ; A61K31/541
摘要：
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I, or pharmaceutically acceptable salts thereof, Formula I or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.
公开/授权文献
- EP3240546B1 TERTIARY ALCOHOL IMIDAZOPYRAZINE BTK INHIBITORS 公开/授权日：2020-10-21
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