发明公开
EP3243385A1 NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
审中-公开
用于抗糖尿病药物的新型环状亚苄基咪唑衍生物
- 专利标题： NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
- 专利标题（中）： 用于抗糖尿病药物的新型环状亚苄基咪唑衍生物
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申请号： EP17173914.7申请日： 2012-02-23
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公开(公告)号： EP3243385A1公开(公告)日： 2017-11-15
- 发明人: ANAND, Rajan , APGAR, James, M. , BIFTU, Tesfaye , CHEN, Ping , CHU, Lin , COLANDREA, Vincent, J. , DONG, Guizhen , DROPINSKI, James, F. , FENG, Danqing , HICKS, Jacqueline, D. , JIANG, Jinlong , KIM, Alexander, J. , LEAVITT, Kenneth, J. , LI, Bing , QIAN, Xiaoxia , SEBHAT, Iyassu , WEI, Lan , WILKENING, Robert, R. , WU, Zhicai
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Hussain, Deeba
- 优先权： US201161446551P 20110225
- 主分类号： A01N43/58
- IPC分类号： A01N43/58
摘要：
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
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