发明公开
- 专利标题： ANTI-ALK2 ANTIBODY
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申请号： EP16743511申请日： 2016-01-29
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公开(公告)号： EP3252074A4公开(公告)日： 2018-07-11
- 发明人: KATAGIRI TAKENOBU , OSAWA KENJI , TSUKAMOTO SHO , TSUJI SHINNOSUKE , KAWAGUCHI YOSHIROU , NAKAMURA KENSUKE
- 申请人： UNIV SAITAMA MEDICAL , DAIICHI SANKYO CO LTD
- 专利权人： UNIV SAITAMA MEDICAL,DAIICHI SANKYO CO LTD
- 当前专利权人： UNIV SAITAMA MEDICAL,DAIICHI SANKYO CO LTD
- 优先权： JP2015017882 2015-01-30
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; A61K45/00 ; A61P19/08 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/09 ; C12P21/08
摘要：
This application provides: an antibody which specifically binds to an ALK2 protein and has an activity of inhibiting BMP signal transduction mediated by ALK2; a method for producing the antibody; and a pharmaceutical composition comprising the antibody, for treating and/or preventing ectopic ossification and/or bone dysplasia, anemia, or diffuse intrinsic pontine glioma (DIPG).
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