The present invention refers to a supply cartridge (1) comprising a support (2) of single portions, provided as a flexible strip-like support, or similar, and presenting a plurality of single dose portions (21) of an edible substance, such as for example coffee, disposed successively along a respective longitudinal direction. In particular, said support (2) of single portions presents a plurality of holes (25) adapted so as to provide a binary code for recognition by a machine (10) for preparing beverages of a set of parameters associated with said supply cartridge (1). The present invention further refers to a machine (10) for preparing beverages, adapted for using a supply cartridge (1), including code apprehension means (7) provided in functional connection with a control device (8) of said machine (10), as well as to a process of preparation of beverages based upon a machine (10) for preparing beverages according to the present invention.