发明公开
- 专利标题: BICYCLIC KETONE SULFONAMIDE COMPOUNDS
- 专利标题(中): 双环酮磺酰胺化合物
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申请号: EP16710566.7申请日: 2016-03-02
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公开(公告)号: EP3265465A1公开(公告)日: 2018-01-10
- 发明人: WEISS, Matthew , MILGRAM, Benjamin C. , DINEEN, Thomas , STELLWAGEN, John , GUZMAN-PEREZ, Angel , BOEZIO, Alessandro , MARX, Isaac E.
- 申请人: Amgen Inc.
- 申请人地址: One Amgen Center Drive Thousand Oaks, CA 91320 US
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: One Amgen Center Drive Thousand Oaks, CA 91320 US
- 代理机构: J A Kemp
- 优先权: US201562127206P 20150302
- 国际公布: WO2016141035 20160909
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/437 ; A61P29/00
摘要:
as defined in the specification, an enantiomer, diastereomer, atropisomer thereof, or a mixture thereof, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders, cough, or itch. Also provided are pharmaceutical compositions containing compounds of the present invention.
公开/授权文献
- EP3265465B1 BICYCLIC KETONE SULFONAMIDE COMPOUNDS 公开/授权日:2019-04-24
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