发明公开
- 专利标题： PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS
- 专利标题（中）： 形成孔的蛋白质共轭物组合物和方法
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申请号： EP16762353.7申请日： 2016-03-08
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公开(公告)号： EP3268050A1公开(公告)日： 2018-01-17
- 发明人: LI, Zengmin , KALACHIKOV, Sergey , JU, Jingyue , FULLER, Carl W.
- 申请人： The Trustees of Columbia University in the City of New York
- 申请人地址： 412 Low Memorial Library 535 West 116th Street New York, New York 10027 US
- 专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人地址： 412 Low Memorial Library 535 West 116th Street New York, New York 10027 US
- 代理机构： Almond-Martin, Carol
- 优先权： US201562130326P 20150309
- 国际公布： WO2016144973 20160915
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; C07D237/26 ; C07D403/04
摘要：
The present disclosure relates to compositions and methods based on a fast, efficient chemical reaction for conjugating a pore-forming protein, such as α-hemolysin, to a biomolecule, such as antibodies, receptors, and enzymes, such as DNA polymerase, and the use of such pore-forming protein conjugates in nanopore devices and methods.
公开/授权文献
- EP3268050B1 PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS 公开/授权日：2021-07-14
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