发明公开
EP3275888A1 PROGESTERONE-CATIONIC LIPID HYBRID AS ANTICANCER AGENT AND THE PROCESS OF SYNTHESIS THEREOF
审中-公开
抗肿瘤药物孕酮 - 阳离子脂质混合物及其合成方法
- 专利标题： PROGESTERONE-CATIONIC LIPID HYBRID AS ANTICANCER AGENT AND THE PROCESS OF SYNTHESIS THEREOF
- 专利标题（中）： 抗肿瘤药物孕酮 - 阳离子脂质混合物及其合成方法
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申请号： EP17179456.3申请日： 2017-07-04
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公开(公告)号： EP3275888A1公开(公告)日： 2018-01-31
- 发明人: MONDAL, Sujan Kumar , JINKA, Sudhakar , BANERJEE, Rajkumar
- 申请人： Council of Scientific & Industrial Research
- 申请人地址： Anusandhan Bhawan Rafi Marg New Delhi 110 001 IN
- 专利权人： Council of Scientific & Industrial Research
- 当前专利权人： Council of Scientific & Industrial Research
- 当前专利权人地址： Anusandhan Bhawan Rafi Marg New Delhi 110 001 IN
- 代理机构： Awapatent AB
- 优先权： IN201611025818 20160728
- 主分类号： C07J41/00
- IPC分类号： C07J41/00 ; A61K31/57 ; A61K35/00
摘要：
The present invention relates to the development of the cationic progesterone compounds of formula 6 as a novel anti-tumor agent. The present invention provides a method for the preparation of novel series of progesterone derivatives of formula 6. The invention also provides information related to highly selective anti-cancer activities of these compounds in wide range of cancer cell irrespective of their progesterone receptor status. Thus, the presently disclosed cationic progesterone compounds offer a viable option as anti-cancer therapeutics.
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