发明公开
EP3277278A1 COMBINATION DOSAGE FORM OF A MU OPIOID RECEPTOR ANTAGONIST AND AN OPIOID AGENT
有权
阿片类药物受体拮抗剂和阿片类药物的联合用药形式
- 专利标题： COMBINATION DOSAGE FORM OF A MU OPIOID RECEPTOR ANTAGONIST AND AN OPIOID AGENT
- 专利标题（中）： 阿片类药物受体拮抗剂和阿片类药物的联合用药形式
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申请号： EP16718062.9申请日： 2016-03-31
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公开(公告)号： EP3277278A1公开(公告)日： 2018-02-07
- 发明人: LI, Shaoling , LEUNG, Manshiu , ZHANG, Hao , THALLADI, Venkat R. , MO, Yun
- 申请人： Theravance Biopharma R&D IP, LLC
- 申请人地址： 901 Gateway Boulevard South San Francisco, CA 94080 US
- 专利权人： Theravance Biopharma R&D IP, LLC
- 当前专利权人： Theravance Biopharma R&D IP, LLC
- 当前专利权人地址： 901 Gateway Boulevard South San Francisco, CA 94080 US
- 代理机构： Abel & Imray
- 优先权： US201562141981P 20150402
- 国际公布： WO2016161069 20161006
- 主分类号： A61K31/439
- IPC分类号： A61K31/439 ; A61K9/24 ; A61K9/28
摘要：
The invention provides a solid composition of the peripheral mu opioid antagonist axelopran and a combination dosage form of the mu opioid antagonist axelopran sulfate in an immediate release form and an opioid analgesic agent which may be in an extended release, sustained release, modified release, or controlled release form and methods of preparing such a combination dosage form.
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