发明公开
- 专利标题: NUCLEIC ACID CONSTRUCT
- 专利标题(中): 核酸构建
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申请号: EP16720483.3申请日: 2016-04-26
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公开(公告)号: EP3288968A1公开(公告)日: 2018-03-07
- 发明人: PULÉ, Martin , CORDOBA, Shaun
- 申请人: UCL Business PLC
- 申请人地址: The Network Building 97 Tottenham Court Road University College London London WC1E 4TP GB
- 专利权人: UCL Business PLC
- 当前专利权人: UCL Business PLC
- 当前专利权人地址: The Network Building 97 Tottenham Court Road University College London London WC1E 4TP GB
- 代理机构: D Young & Co LLP
- 优先权: GB201507104 20150427
- 国际公布: WO2016174408 20161103
- 主分类号: C07K14/705
- IPC分类号: C07K14/705 ; C07K16/28 ; C12N15/85
摘要:
The present invention provides a nucleic acid construct comprising the following structure: A-X-B in which A and B are nucleic acid sequences encoding a first and a second polypeptide of interest (POI); and X is a nucleic acid sequence which encodes a cleavage site, wherein either the first or second POI is a transmembrane protein which comprises an intracellular retention signal.
公开/授权文献
- EP3288968B1 NUCLEIC ACID CONSTRUCT 公开/授权日:2020-11-25
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