发明公开
EP3288968A1 NUCLEIC ACID CONSTRUCT 审中-公开
核酸构建

  • 专利标题: NUCLEIC ACID CONSTRUCT
  • 专利标题(中): 核酸构建
  • 申请号: EP16720483.3
    申请日: 2016-04-26
  • 公开(公告)号: EP3288968A1
    公开(公告)日: 2018-03-07
  • 发明人: PULÉ, MartinCORDOBA, Shaun
  • 申请人: UCL Business PLC
  • 申请人地址: The Network Building 97 Tottenham Court Road University College London London WC1E 4TP GB
  • 专利权人: UCL Business PLC
  • 当前专利权人: UCL Business PLC
  • 当前专利权人地址: The Network Building 97 Tottenham Court Road University College London London WC1E 4TP GB
  • 代理机构: D Young & Co LLP
  • 优先权: GB201507104 20150427
  • 国际公布: WO2016174408 20161103
  • 主分类号: C07K14/705
  • IPC分类号: C07K14/705 C07K16/28 C12N15/85
NUCLEIC ACID CONSTRUCT
摘要:
The present invention provides a nucleic acid construct comprising the following structure: A-X-B in which A and B are nucleic acid sequences encoding a first and a second polypeptide of interest (POI); and X is a nucleic acid sequence which encodes a cleavage site, wherein either the first or second POI is a transmembrane protein which comprises an intracellular retention signal.
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