发明公开
- 专利标题： AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES
- 专利标题（中）： 酰胺取代的环己烷衍生物
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申请号： EP16721762.9申请日： 2016-05-02
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公开(公告)号： EP3292107A1公开(公告)日： 2018-03-14
- 发明人: EIS, Knut , ACKERSTAFF, Jens , WAGNER, Sarah , BUCHGRABER, Philipp , SÜLZLE, Detlev , HOLTON, Simon , BENDER, Eckhard , LI, Volkhart , LIU, Ningshu , SIEGEL, Franziska , LIENAU, Philip , BAIRLEIN, Michaela , VON NUSSBAUM, Franz , HERBERT,Simon , KOPPITZ, Marcus
- 申请人： Bayer Pharma Aktiengesellschaft
- 申请人地址： Müllerstrasse 178 13353 Berlin DE
- 专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人地址： Müllerstrasse 178 13353 Berlin DE
- 代理机构： BIP Patents
- 优先权： EP15166484 20150505
- 国际公布： WO2016177658 20161110
- 主分类号： C07D233/54
- IPC分类号： C07D233/54 ; C07D263/34 ; C07D401/12 ; C07D403/06 ; C07D405/12 ; C07D413/06 ; C07D417/06 ; C07D487/14 ; A61K31/38 ; A61K31/4164 ; A61K31/421 ; A61K31/5025 ; A61P35/00
摘要：
The present invention relates to amido-substituted cyclohexane compounds of general formula (I), in which A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredient.
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