发明公开
EP3302709A2 METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION
审中-公开
RNA引导治疗HIV感染的方法和组合物
- 专利标题: METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION
- 专利标题(中): RNA引导治疗HIV感染的方法和组合物
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申请号: EP16804274.5申请日: 2016-06-01
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公开(公告)号: EP3302709A2公开(公告)日: 2018-04-11
- 发明人: KHALILI, Kamel , HU, Wenhui , ZHANG, Yonggang
- 申请人: Temple University - Of The Commonwealth System of Higher Education
- 申请人地址: Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 专利权人: Temple University - Of The Commonwealth System of Higher Education
- 当前专利权人: Temple University - Of The Commonwealth System of Higher Education
- 当前专利权人地址: Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 代理机构: HGF Limited
- 优先权: US201562169384P 20150601; US201562169633P 20150602; US201662308320P 20160315
- 国际公布: WO2016196539 20161208
- 主分类号: A61P31/18
- IPC分类号: A61P31/18 ; A61K48/00 ; C12N5/10 ; C12N15/63 ; C12N9/22
摘要:
Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome.
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