A tamper seal detection system for detecting a sealing sticker on a packaging box incudes a housing at least partially bounding an inspection zone, the inspection zone being configured to receive the packaging box. A first sensor is configured to detect the presence of the first sealing sticker located on the packaging box when the packaging box is received within the inspection zone. A push guide is movable relative to the inspection floor between a first position and a spaced apart second position and can be used to push the packaging box out of the inspection zone.