发明公开
- 专利标题: METHODS FOR OBTAINING REGULATORY T CELLS AND USES THEREOF
- 专利标题(中): 获得调节T细胞的方法及其用途
-
申请号: EP16734644.4申请日: 2016-07-01
-
公开(公告)号: EP3317398A1公开(公告)日: 2018-05-09
- 发明人: GUILLONNEAU, Carole , ANEGON, Ignacio , BEZIE, Séverine
- 申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Universite de Nantes , Centre Hospitalier Universitaire De Nantes
- 申请人地址: 101, rue de Tolbiac 75013 Paris FR
- 专利权人: INSERM (Institut National de la Santé et de la Recherche Médicale),Universite de Nantes,Centre Hospitalier Universitaire De Nantes
- 当前专利权人: INSERM (Institut National de la Santé et de la Recherche Médicale),Universite de Nantes,Centre Hospitalier Universitaire De Nantes
- 当前专利权人地址: 101, rue de Tolbiac 75013 Paris FR
- 代理机构: Icosa
- 优先权: EP15306092 20150703
- 国际公布: WO2017005647 20170112
- 主分类号: C12N5/0783
- IPC分类号: C12N5/0783 ; C12N5/0786
摘要:
Disclosed is a method for obtaining a population of human Treg cells including the steps of: (a) culturing a population of human monocytes with a medium including an amount of an interleukin-34 (IL-34) polypeptide in order to obtain a population of immunosuppressive macrophages; (b) co-culturing a population of human peripheral blood mononuclear cells (PBMCs) and the population of immunosuppressive macrophages obtained at step (a).
信息查询