- 专利标题: IMMUNE ENHANCING RECOMBINANT DENGUE PROTEIN
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申请号: EP16833671.7申请日: 2016-08-01
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公开(公告)号: EP3331559A1公开(公告)日: 2018-06-13
- 发明人: SIMMONS, Monika , PUTNAK, Joseph, R.
- 申请人: The United States of America as represented by the Secretary of the Army, Walter Reed Army Institute Of Research (WRAIR) , The United States of America as Represented by the Secretary of the Navy
- 申请人地址: 503 Robert Grant Ave. Silber Spring MD 20910 US
- 专利权人: The United States of America as represented by the Secretary of the Army, Walter Reed Army Institute Of Research (WRAIR),The United States of America as Represented by the Secretary of the Navy
- 当前专利权人: The United States of America as represented by the Secretary of the Army, Walter Reed Army Institute Of Research (WRAIR),The United States of America as Represented by the Secretary of the Navy
- 当前专利权人地址: 503 Robert Grant Ave. Silber Spring MD 20910 US
- 代理机构: Cabinet Beau de Loménie
- 优先权: US201562200263P 20150803
- 国际公布: WO2017023839 20170209
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; C07K1/00 ; C07H21/04
摘要:
The invention relates to a method for preventing, ameliorating or treating disease caused by dengue virus in a subject in need thereof comprising administering to the subject a dengue vaccine formulation in combination with a NS3 helicase polypeptide and/or fragment(s) thereof, wherein said method comprises stimulating humoral as well as cell-mediated immunity to the dengue virus in the subject.
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