发明公开
- 专利标题： COMPOUNDS AND METHODS USEFUL FOR TREATING OR PREVENTING HEMATOLOGICAL CANCERS
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申请号： EP16762989.8申请日： 2016-08-29
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公开(公告)号： EP3344243A1公开(公告)日： 2018-07-11
- 发明人: SYKES, David B. , SCADDEN, David , LEWIS, Timothy A. , JANZER, Andreas , MEYER, Hanna , STÖCKIGT, Detlef
- 申请人： The Broad Institute Inc. , The General Hospital Corporation , BAYER PHARMA AKTIENGESELLSCHAFT , President and Fellows of Harvard College
- 申请人地址： 415 Main Street Cambridge, MA 02142 US
- 专利权人： The Broad Institute Inc.,The General Hospital Corporation,BAYER PHARMA AKTIENGESELLSCHAFT,President and Fellows of Harvard College
- 当前专利权人： The Broad Institute Inc.,The General Hospital Corporation,BAYER PHARMA AKTIENGESELLSCHAFT,President and Fellows of Harvard College
- 当前专利权人地址： 415 Main Street Cambridge, MA 02142 US
- 代理机构： BIP Patents
- 优先权： US201562212992P 20150901; US201662329796P 20160429
- 国际公布： WO2017037022 20170309
- 主分类号： A61K31/27
- IPC分类号： A61K31/27 ; A61K31/42 ; A61K31/505 ; A61P35/02
摘要：
The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with DHODH inhibitors, such as 6-fluoro-2-(2′-fluoro-[1,1′-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid).
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