- 专利标题: HETEROBICYCLIC PYRIMIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
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申请号: EP16843038.7申请日: 2016-09-02
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公开(公告)号: EP3344632A1公开(公告)日: 2018-07-11
- 发明人: SKERLJ, Renato, T. , GOOD, Andrew, C. , LANSBURY, Peter, T.
- 申请人: Lysosomal Therapeutics Inc.
- 申请人地址: 19 Blackstone Street Cambridge, MA 02139 US
- 专利权人: Lysosomal Therapeutics Inc.
- 当前专利权人: Lysosomal Therapeutics Inc.
- 当前专利权人地址: 19 Blackstone Street Cambridge, MA 02139 US
- 代理机构: Kirkham, Nicholas Andrew
- 优先权: US201562214478P 20150904
- 国际公布: WO2017040877 20170309
- 主分类号: C07D513/04
- IPC分类号: C07D513/04 ; C07D498/04 ; C07D471/04 ; A61K31/542 ; A61K31/4985 ; A61P25/16 ; A61P3/10 ; A61P13/12 ; A61P25/08 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P27/06 ; A61P43/00 ; A61P35/00 ; A61P25/00
摘要:
The invention provides heterobicyclic pyrimidinone compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary heterobicyclic pyrimidinone compounds described herein include 6-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b)][1,3]thiazine-7-carboxamide compounds.
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