发明公开
- 专利标题： POTENTIATOR-CORRECTOR COMBINATIONS USEFUL IN THE TREATMENT OF CYSTIC FIBROSIS
-
申请号： EP16790700.5申请日： 2016-10-07
-
公开(公告)号： EP3359144A1公开(公告)日： 2018-08-15
- 发明人: CONRATH, Katja E. , ROWE, Steven M.
- 申请人： AbbVie S.À.R.L. , Galapagos NV
- 申请人地址： 26 Boulevard Royal 2449 Luxembourg LU
- 专利权人： AbbVie S.À.R.L.,Galapagos NV
- 当前专利权人： AbbVie S.À.R.L.,Galapagos NV
- 当前专利权人地址： 26 Boulevard Royal 2449 Luxembourg LU
- 代理机构： J A Kemp
- 优先权： US201562239667P 20151009
- 国际公布： WO2017060880 20170413
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; C12Q1/68
摘要：
A combination therapy including a modulator of the function (potentiator) of cystic fibrosis transmembrane conductance regulator (CFTR) protein, and one or two modulator(s) of the cellular processing and/or localization molecule (correctors) is provided in a method for treating cystic fibrosis in a subject having a mutation located between the amino acid residues 1164-1480 of full length wild-type CFTR.
信息查询
