- 专利标题: FOXM1-DERIVED PEPTIDE, AND VACCINE INCLUDING SAME
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申请号: EP16853677.9申请日: 2016-10-06
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公开(公告)号: EP3360886A1公开(公告)日: 2018-08-15
- 发明人: YAMASHITA, Sachiko , HIKICHI, Tetsuro
- 申请人: Oncotherapy Science, Inc.
- 申请人地址: 2-1, Sakado 3-chome Takatsu-ku Kawasaki-shi Kanagawa 213-0012 JP
- 专利权人: Oncotherapy Science, Inc.
- 当前专利权人: Oncotherapy Science, Inc.
- 当前专利权人地址: 2-1, Sakado 3-chome Takatsu-ku Kawasaki-shi Kanagawa 213-0012 JP
- 代理机构: Zacco GmbH
- 优先权: JP2015200221 20151008
- 国际公布: WO2017061523 20170413
- 主分类号: C07K7/06
- IPC分类号: C07K7/06 ; A61K35/12 ; A61K35/17 ; A61K38/00 ; A61K48/00 ; A61P1/04 ; A61P1/16 ; A61P1/18 ; A61P11/00 ; A61P13/08 ; A61P13/10 ; A61P13/12 ; A61P15/00 ; A61P19/00 ; A61P35/00 ; A61P35/02 ; A61P37/04 ; C12N5/10 ; C12N15/09 ; G01N33/15 ; G01N33/50
摘要:
The present invention provides FOXM1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
公开/授权文献
- EP3360886B1 FOXM1-DERIVED PEPTIDE, AND VACCINE INCLUDING SAME 公开/授权日:2023-01-25
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