- 专利标题： 6-[5-AMINO-6-(2-ETHOXYETHOXY)-IMIDAZO[4,5-B]PYRIDIN-3-YL]-NICOTINONITRILE DERIVATIVES AND THEIR USE AS IRAK INHIBITORS
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申请号： EP16794525.2申请日： 2016-10-14
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公开(公告)号： EP3365341A1公开(公告)日： 2018-08-29
- 发明人: BRYS, Reginald, Christophe, Xavier , GENEY, Raphaël, Jean, Joël , JONCOUR, Agnès, Marie , DOYON, Julien, Georges, Pierre-Olivier , LABÉGUÈRE, Frédéric, Gilbert , LEFRANCOIS, Jean-Michel , MAMMOLITI, Oscar , SCHMITT, Benoît, Antoine , VAN DER PLAS, Steven, Emiel , MENET, Christel, Jeanne, Marie
- 申请人： Galapagos N.V.
- 申请人地址： Generaal de Wittelaan L11 A3 2800 Mechelen BE
- 专利权人： Galapagos N.V.
- 当前专利权人： Galapagos N.V.
- 当前专利权人地址： Generaal de Wittelaan L11 A3 2800 Mechelen BE
- 代理机构： Bar, Grégory
- 优先权： GB201518456 20151019
- 国际公布： WO2017067848 20170427
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P29/00 ; A61P35/00 ; A61P37/00
摘要：
The present invention relates to compounds inhibiting IRAK family kinases, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases and/or proliferative diseases by administering the compound of the invention.
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