• 专利标题: IMMUNOSTIMULATING-TOXIC RNA IN ALKALINE EARTH METAL FORMULATION
  • 申请号: EP16785159.1
    申请日: 2016-10-21
  • 公开(公告)号: EP3365444A1
    公开(公告)日: 2018-08-29
  • 发明人: PASCOLO, Steve
  • 申请人: spRNA GmbH
  • 申请人地址: Kanzleistrasse 231 8004 Zürich CH
  • 专利权人: spRNA GmbH
  • 当前专利权人: spRNA GmbH
  • 当前专利权人地址: Kanzleistrasse 231 8004 Zürich CH
  • 代理机构: Habermann, Hruschka & Schnabel
  • 优先权: EP15190920 20151021
  • 国际公布: WO2017068156 20170427
  • 主分类号: C12N15/11
  • IPC分类号: C12N15/11
IMMUNOSTIMULATING-TOXIC RNA IN ALKALINE EARTH METAL FORMULATION
摘要:
A composition including an immunostimulating RNA molecule in a dication containing solution wherein the RNA includes a chemical modification which is toxic to cancer or tumor cells. Pharmaceutical compositions incorporate the immunostimulating RNA with tumor cytotoxicity. Methods for treating cancer and tumors use the solution of the immunostimulating RNA with tumor cytotoxicity.
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