- 专利标题: SUPERSATURATED COMPOSITIONS OF BENZIMIDAZOLE COMPOUNDS
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申请号: EP16797944.2申请日: 2016-11-18
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公开(公告)号: EP3377479A1公开(公告)日: 2018-09-26
- 发明人: HERNÁNDEZ HERRERO, Gonzalo , RUBIO ROYO, Víctor , GARCÍA DOMÍNGUEZ, Neftalí , CANAL MORI, Gonzalo , TESSON, Nicolas
- 申请人: FAES FARMA, S.A.
- 申请人地址: Autonomía, 10 48940 Leioa - Vizcaya ES
- 专利权人: FAES FARMA, S.A.
- 当前专利权人: FAES FARMA, S.A.
- 当前专利权人地址: Autonomía, 10 48940 Leioa - Vizcaya ES
- 代理机构: ABG Patentes, S.L.
- 优先权: EP15382574 20151120
- 国际公布: WO2017085265 20170526
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; A61K31/445 ; A61P37/08
摘要:
The invention relates to a stable supersaturated aqueous solution comprising a benzimidazole compound of formula (I) and an organic carboxylic acid selected from the group consisting of substituted or unsubstituted aliphatic C 3 -C 8 ±,É-dicarboxylic acids and substituted or unsubstituted aliphatic C 2 -C 6 monocarboxylic acids and to its use in the treatment and/or prevention of conditions mediated by H 1 histamine receptor, such as allergic disorders or diseases. The invention also relates to the use of the above organic carboxylic acids to increase the aqueous solubility of benzimidazole compounds of formula (I).
公开/授权文献
- EP3377479B1 SUPERSATURATED COMPOSITIONS OF BENZIMIDAZOLE COMPOUNDS 公开/授权日:2020-01-29
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