SUPERSATURATED COMPOSITIONS OF BENZIMIDAZOLE COMPOUNDS
摘要:
The invention relates to a stable supersaturated aqueous solution comprising a benzimidazole compound of formula (I) and an organic carboxylic acid selected from the group consisting of substituted or unsubstituted aliphatic C 3 -C 8 ±,É-dicarboxylic acids and substituted or unsubstituted aliphatic C 2 -C 6 monocarboxylic acids and to its use in the treatment and/or prevention of conditions mediated by H 1 histamine receptor, such as allergic disorders or diseases. The invention also relates to the use of the above organic carboxylic acids to increase the aqueous solubility of benzimidazole compounds of formula (I).
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