- 专利标题: ACRYLIC ACID DERIVATIVE, PREPARATION METHOD AND USE IN MEDICINE THEREOF
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申请号: EP16863515.9申请日: 2016-10-11
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公开(公告)号: EP3378861A1公开(公告)日: 2018-09-26
- 发明人: GUAN, Dongliang , SHENG, Shouyi , BAI, Hua
- 申请人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 申请人地址: 46, Waisha Road Jiaojiang District Taizhou Zhejiang 318000 CN
- 专利权人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人: Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人地址: 46, Waisha Road Jiaojiang District Taizhou Zhejiang 318000 CN
- 代理机构: Kador & Partner PartG mbB
- 优先权: CN201510771111 20151112
- 国际公布: WO2017080338 20170518
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/437 ; A61K31/444 ; A61P35/00
摘要:
The present invention relates to an acrylic acid derivative as shown in general formula (I), a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, the preparation method thereof, a pharmaceutical composition containing same, and the use thereof as therapeutic agents, in particular as selective estrogen receptor degraders (SERD), wherein the substituents of general formula (I) are the same as those defined in the description.
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