- 专利标题： PEPTIDES DERIVED FROM HOMEOBOX PROTEIN B13 (HOX-B13) AND COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES
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申请号： EP16805195.1申请日： 2016-11-23
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公开(公告)号： EP3380504A1公开(公告)日： 2018-10-03
- 发明人: POWLESLAND, Alex , SUN, Meidai
- 申请人： Immunocore Limited , Adaptimmune Limited
- 申请人地址： 101 Park Drive Milton Park Abingdon, Oxfordshire OX14 4RY GB
- 专利权人： Immunocore Limited,Adaptimmune Limited
- 当前专利权人： Immunocore Limited,Adaptimmune Limited
- 当前专利权人地址： 101 Park Drive Milton Park Abingdon, Oxfordshire OX14 4RY GB
- 代理机构： Lee, Nicholas John
- 优先权： GB201520557 20151123
- 国际公布： WO2017089778 20170601
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; A61K39/00 ; C07K4/12
摘要：
The present invention relates to novel peptides derived from Homeobox protein Hox-B13 (HOXB13), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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