- 专利标题： MEANS AND METHODS FOR TREATING COPPER-RELATED DISEASES
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申请号： EP16823220.5申请日： 2016-12-16
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公开(公告)号： EP3389648A2公开(公告)日： 2018-10-24
- 发明人: ZISCHKA, Hans , LICHTMANNEGGER, Josef , DISPIRITO, Alan, Angelo , SEMRAU, Jeremy, David
- 申请人： Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) , The Regents of The University of Michigan , Iowa State University Research Foundation, Inc.
- 申请人地址： Ingolstädter Landstrasse 1 85764 Neuherberg DE
- 专利权人： Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH),The Regents of The University of Michigan,Iowa State University Research Foundation, Inc.
- 当前专利权人： Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH),The Regents of The University of Michigan,Iowa State University Research Foundation, Inc.
- 当前专利权人地址： Ingolstädter Landstrasse 1 85764 Neuherberg DE
- 代理机构： Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
- 优先权： EP15201070 20151218; LU92979 20160219
- 国际公布： WO2017103094 20170622
- 主分类号： A61K31/30
- IPC分类号： A61K31/30 ; A61K38/00 ; A61K31/315 ; A61K31/4166 ; A61P1/16
摘要：
The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions.
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