- 专利标题： CD24HICD38HI TRANSITIONAL B CELLS AND CD9 AS NEW BIOMARKER OF LONG-TERM HUMAN LUNG ALLOGRAFT SURVIVAL
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申请号： EP17305479.2申请日： 2017-04-28
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公开(公告)号： EP3396377A1公开(公告)日： 2018-10-31
- 发明人: BROSSEAU, Carole , DURAND, Maxim , MAGNAN, Antoine , BROUARD, Sophie
- 申请人： Universite de Nantes , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CHU Nantes
- 申请人地址： 1, quai de Tourville 44000 Nantes FR
- 专利权人： Universite de Nantes,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),CHU Nantes
- 当前专利权人： Universite de Nantes,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),CHU Nantes
- 当前专利权人地址： 1, quai de Tourville 44000 Nantes FR
- 代理机构： Nony
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; G01N33/569
摘要：
The present invention relates to an in vitro method for determining the risk of occurrence of chronic lung graft dysfunction in a human subject comprising:
a) measuring the level of CD9 + B cells in a blood sample of the subject,
b) comparing the level of CD9 + B cells measured at step a) with one or more reference values of the level of CD9 + B cells, and
c) determining the risk of occurrence of chronic lung graft dysfunction in the said subject from the comparison performed at step b).
a) measuring the level of CD9 + B cells in a blood sample of the subject,
b) comparing the level of CD9 + B cells measured at step a) with one or more reference values of the level of CD9 + B cells, and
c) determining the risk of occurrence of chronic lung graft dysfunction in the said subject from the comparison performed at step b).
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