Multiplexed unequal error protection for wireless networks is disclosed. A device may determine reliability associated with a first subcarrier of a channel including the first subcarrier and at least one second subcarrier. The reliability of the first subcarrier may be determined based on the position of the first subcarrier relative to each at least one second subcarrier. High priority data may be assigned to the first subcarrier for transmission if the first subcarrier is determined to have a higher reliability than the at least one second subcarrier. For example, the channel may be an orthogonal frequency division multiplexed (OFDM) channel and higher reliability may be associated with a first subcarrier that is in a middle position of the plurality of subcarriers within the OFDM channel. In another example, higher reliability may be associated with a first OFDM subcarrier that is adjacent to an unused OFDM channel bandwidth.