This application provides a device and a method for supporting clock transfer of multiple clock domains. The device includes: N phase frequency detectors, N filters, N clock reconstructors, and N clock domain interfaces, where N is an integer greater than or equal to 2, the N clock domain interfaces are in a one-to-one correspondence with the N phase frequency detectors, the N filters, and the N clock reconstructors, the N phase frequency detectors are respectively connected to N clock sources, and at least two clock sources of the N clock sources are different. The foregoing device can reconstruct multiple different clock signals by transferring a common reference clock signal, digitized phase difference information, and frequency difference information, and apply the clock signals to clock domain interfaces of various clock domains, so as to flexibly adapt to multiple different clock domains, implement that a single device simultaneously supports clock transfer of multiple clock domains, and flexibly satisfy user demands without adding or replacing devices.