- 专利标题： KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS
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申请号： EP18185054.6申请日： 2010-06-22
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公开(公告)号： EP3409765A2公开(公告)日： 2018-12-05
- 发明人: BONG, Yong Koy , VOGEL, Michael , COLLIER, Steven, James , MITCHELL, Vesna , MAVINAHALLI, Jagadeesh
- 申请人： Codexis, Inc.
- 申请人地址： 200 Penobscot Drive Redwood City, CA 94063 US
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： 200 Penobscot Drive Redwood City, CA 94063 US
- 代理机构： Chapman, Desmond Mark
- 优先权： US21916209P 20090622; US30305710P 20100210
- 主分类号： C12N9/02
- IPC分类号： C12N9/02 ; C12N15/53 ; A61P7/04 ; C12P7/28 ; C12P13/02 ; C12P17/02
摘要：
The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α-chloroalcohols from α-chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.
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