发明公开
- 专利标题： METHODS FOR TREATING DLBCL
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申请号： EP18164175.4申请日： 2011-10-27
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公开(公告)号： EP3412687A1公开(公告)日： 2018-12-12
- 发明人: ZUGMAIER, Gerhard , NAGORSEN, Dirk , SCHEELE, Juergen
- 申请人： Amgen Research (Munich) GmbH
- 申请人地址： Staffelseestrasse 2 81477 München DE
- 专利权人： Amgen Research (Munich) GmbH
- 当前专利权人： Amgen Research (Munich) GmbH
- 当前专利权人地址： Staffelseestrasse 2 81477 München DE
- 代理机构： Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
- 优先权： US40710710P 20101027
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/46 ; A61K39/395 ; A61P35/00
摘要：
The present invention provides means and methods for treating diffuse large B cell lymphoma (DLBCL). Specifically, a bispecific CD19 x CD3 antibody which engages T cells via its CD3 binding portion and concomitantly binds to CD19 on the surface of, in particular, lymphoma cells via its CD19 binding portion (i.e. a bispecific T cell engager, "BiTE") is administered for use in the treatment of tumorous mass of lymophoreticular tissue and/or extranodal lymphoma caused by DLBCL in a patient.
公开/授权文献
- EP3412687B1 METHODS FOR TREATING DLBCL 公开/授权日：2020-03-18
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