- 专利标题: TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR
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申请号: EP17752706.6申请日: 2017-02-20
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公开(公告)号: EP3418282A1公开(公告)日: 2018-12-26
- 发明人: LIU, Shilan , WANG, Dahai , LIANG, Guibai , HU, Guoping , LI, Jian , CHEN, Shuhui
- 申请人: Chai Tai Tianqing Pharmaceutical Group Co., Ltd. , Medshine Discovery Inc.
- 申请人地址: No.369 Yuzhou South Road Haizhou District Lianyungang Jiangsu 222062 CN
- 专利权人: Chai Tai Tianqing Pharmaceutical Group Co., Ltd.,Medshine Discovery Inc.
- 当前专利权人: Chai Tai Tianqing Pharmaceutical Group Co., Ltd.,Medshine Discovery Inc.
- 当前专利权人地址: No.369 Yuzhou South Road Haizhou District Lianyungang Jiangsu 222062 CN
- 代理机构: Gulde & Partner
- 优先权: CN201610094757 20160219; CN201610247693 20160420; CN201610324408 20160516; CN201610821994 20160913
- 国际公布: WO2017140274 20170824
- 主分类号: C07D487/14
- IPC分类号: C07D487/14 ; C07D495/14 ; A61P37/06
摘要:
Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.
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