- 专利标题: CRYSTALS OF NOVEL HYDROXAMIC ACID DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION
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申请号: EP17775419.9申请日: 2017-03-30
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公开(公告)号: EP3438088A1公开(公告)日: 2019-02-06
- 发明人: BABA, Yasutaka , NAGATO, Yusuke , KOSEKI, Yu
- 申请人: Toyama Chemical Co., Ltd.
- 申请人地址: 2-5 Nishishinjuku 3-Chome Shinjuku-ku Tokyo 160-0023 JP
- 专利权人: Toyama Chemical Co., Ltd.
- 当前专利权人: Toyama Chemical Co., Ltd.
- 当前专利权人地址: 2-5 Nishishinjuku 3-Chome Shinjuku-ku Tokyo 160-0023 JP
- 代理机构: Hoffmann Eitle
- 优先权: JP2016070504 20160331
- 国际公布: WO2017170885 20171005
- 主分类号: C07C239/08
- IPC分类号: C07C239/08 ; A61K31/166 ; A61P31/04 ; A61P43/00
摘要:
Crystals of (2S)-2-((4-((4-((1S)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N',2-dimethylmalonamide having diffraction peaks at diffraction angles (2θ) of 3.8 ± 0.2°, 7.7 ± 0.2°, and 10.8 ± 0.2°, etc., or 8.2 ± 0.2°, 12.4 ± 0.2°, and 13.3 ± 0.2°, etc., in powder X-ray diffraction, a production method thereof, and a pharmaceutical composition.
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