发明公开
- 专利标题： PROCESS AND INTERMEDIATES FOR THE 6,7-ALPHA-EPOXIDATION OF STEROID 4,6-DIENES
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申请号： EP17725742.5申请日： 2017-05-18
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公开(公告)号： EP3458467A1公开(公告)日： 2019-03-27
- 发明人: WEYMOUTH-WILSON, Alexander Charles , KOMSTA, Zofia , WALLIS, Laura , EVANS, Timothy
- 申请人： NZP UK Limited
- 申请人地址： One, Glass Wharf Bristol, BS2 0ZX GB
- 专利权人： NZP UK Limited
- 当前专利权人： NZP UK Limited
- 当前专利权人地址： One, Glass Wharf Bristol, BS2 0ZX GB
- 代理机构： O'Kane, Jessica Ann
- 优先权： GB201608776 20160518
- 国际公布： WO2017199036 20171123
- 主分类号： C07J9/00
- IPC分类号： C07J9/00 ; C07J71/00
摘要：
The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein, wherein the epoxidation is conducted using an oxidant and methyltrioxorhenium as a catalyst (MeReO3). The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis of synthetic bile acids.
公开/授权文献
- EP3458467B1 PROCESS FOR THE 6,7-ALPHA-EPOXIDATION OF STEROID 4,6-DIENES 公开/授权日：2020-09-30
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