- 专利标题： 9-SUBSTITUTED MINOCYCLINE COMPOUNDS
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申请号： EP18187132.8申请日： 2001-06-29
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公开(公告)号： EP3461808A1公开(公告)日： 2019-04-03
- 发明人: NELSON, Mark. L. , FRECHETTE, Roger , VISKI, Peter , ISMAIL, Mohamed, Y. , BOWSER, Todd , DUMORNAY, Jimmy , RENNIE, Glen , LIU, Gui , KOZA, Darrell , SHEANAN, Paul , STAPLETON, Karen , HAWKINS, Paul , BHATIA, Beena , VERMA, Atul , HONEYMAN, Laura , WARCHOL, Ted
- 申请人： Trustees of Tufts College , Paratek Pharmaceuticals, Inc.
- 申请人地址： Tufts University Ballou Hall, 4th Floor Medford, Massachusetts 02155 US
- 专利权人： Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- 当前专利权人： Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- 当前专利权人地址： Tufts University Ballou Hall, 4th Floor Medford, Massachusetts 02155 US
- 代理机构： Haseltine Lake LLP
- 优先权： US216659P 20000707; US275621P 20010313
- 主分类号： C07C237/26
- IPC分类号： C07C237/26 ; A61K31/65
摘要：
The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
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