- 专利标题: FACTOR VIII VARIANTS HAVING A DECREASED CELLULAR UPTAKE
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申请号: EP18195448.8申请日: 2011-09-14
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公开(公告)号: EP3466968A1公开(公告)日: 2019-04-10
- 发明人: MEEMS, Henriët , MEIJER, Alexander Benjamin , MERTENS, Koenraad , OLSEN, Ole Hvilsted , LAMBERTH, Kasper , NOERBY, Peder Lisby , JOHNSEN, Laust Bruun , KJALKE, Marianne , STENNICKE, Henning Ralf , VOORBERG, Johannes Jacobus , VAN DEN BIGGELAAR, Maartje
- 申请人: Stichting Sanquin Bloedvoorziening
- 申请人地址: Plesmanlaan 125 1066 CX Amsterdam NL
- 专利权人: Stichting Sanquin Bloedvoorziening
- 当前专利权人: Stichting Sanquin Bloedvoorziening
- 当前专利权人地址: Plesmanlaan 125 1066 CX Amsterdam NL
- 代理机构: V.O.
- 优先权: EP10176731 20100915; US38473110P 20100921; EP11173768 20110713; US201161507666P 20110714
- 主分类号: C07K14/755
- IPC分类号: C07K14/755 ; A61K38/00
摘要:
The present invention relates to modified coagulation factors. In particular, the present invention relates to modied Factor VIII molecules having decreased cellular uptake.
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