- 专利标题： FUSION PROTEIN FOR IMPROVING PROTEIN EXPRESSION FROM TARGET mRNA
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申请号： EP17806675.9申请日： 2017-05-30
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公开(公告)号： EP3466978A1公开(公告)日： 2019-04-10
- 发明人: NAKAMURA, Takahiro , YAGI, Yusuke
- 申请人： Kyushu University, National University Corporation
- 申请人地址： 744, Motooka Nishi-ku Fukuoka-shi Fukuoka 819-0395 JP
- 专利权人： Kyushu University, National University Corporation
- 当前专利权人： Kyushu University, National University Corporation
- 当前专利权人地址： 744, Motooka Nishi-ku Fukuoka-shi Fukuoka 819-0395 JP
- 代理机构： Weickmann & Weickmann PartmbB
- 优先权： US201662345252P 20160603; JP2016120524 20160617
- 国际公布： WO2017209122 20171207
- 主分类号： C07K19/00
- IPC分类号： C07K19/00 ; C07K14/415 ; C07K14/435 ; C12N15/09
摘要：
[Problem to be Solved] The object of the present invention is to develop a method of regulating a target RNA.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.
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