- 专利标题： CONDENSED THIOPHENE DERIVATIVES USEFUL AS NAPI-IIB INHIBITORS
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申请号： EP17754914.4申请日： 2017-08-08
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公开(公告)号： EP3497091A1公开(公告)日： 2019-06-19
- 发明人: COATES, David Andrew , FALES, Kevin Robert , PETERSON, Jeffrey Alan , SCHKERYANTZ, Jeffrey Michael , SHEN, Quanrong , VALLI, Matthew John , WETTERAU II, John Rowley , WODKA, Dariusz Stanislaw , XU, Yangping
- 申请人： Eli Lilly and Company
- 申请人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 代理机构： Bassinder, Emma Marie
- 优先权： US201662375169P 20160815
- 国际公布： WO2018034883 20180222
- 主分类号： C07D333/66
- IPC分类号： C07D333/66 ; A61K31/381 ; A61K31/496 ; A61K31/4995 ; C07D471/10 ; A61P9/00 ; A61P13/12
摘要：
The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular diease associated with chronic kidney disease.
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