- 专利标题: CLOTTING FACTOR-FC CHIMERIC PROTEINS TO TREAT HEMOPHILIA
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申请号: EP19157022.5申请日: 2004-05-06
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公开(公告)号: EP3552627A1公开(公告)日: 2019-10-16
- 发明人: RIVERA, Daniel S. , PETERS, Robert T. , BITONTI, Alan J.
- 申请人: Bioverativ Therapeutics Inc.
- 申请人地址: 225 Second Avenue Waltham MA 02451 US
- 专利权人: Bioverativ Therapeutics Inc.
- 当前专利权人: Bioverativ Therapeutics Inc.
- 当前专利权人地址: 225 Second Avenue Waltham MA 02451 US
- 代理机构: Böhmer, Thomas
- 优先权: US46883703P 20030506
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12P21/08 ; A61K38/36 ; C07K14/745 ; C07K16/18 ; A61K45/06 ; C12N9/64 ; A61K39/00 ; A61K38/48
摘要:
A pharmaceutical composition, for treatment of a hemostatic disorder, comprises a chimeric protein and a pharmaceutically acceptable carrier or excipient, wherein said chimeric protein comprises at least a portion of an immunoglobulin constant region which is an FcRn binding partner, a clotting factor selected from Factor VII, a Factor VII analog, Factor VIIa and a Factor VIIa analog, and optionally at least one linker.
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