- 专利标题： A GOLD(III) COMPLEX, A CONJUGATE OF THE GOLD(III) COMPLEX, A PHARMACEUTICAL COMPOSITION COMPRISING THE GOLD(III) COMPLEX AND USES AND A PROCESS FOR PREPARING THE GOLD(III) COMPLEX
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申请号： EP18382305.3申请日： 2018-05-03
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公开(公告)号： EP3564246A1公开(公告)日： 2019-11-06
- 发明人: SOTO GONZÁLEZ, Sara María , RATIA LONCÁN, Carlos , CEPAS LÓPEZ, Virginio , LÓPEZ CUBILLOS, Yuly , LÓPEZ ORTIZ, Fernando , IGLESIAS VALDÉS-SOLÍS, María José , GONZÁLEZ SOENGAS, Raquel María
- 申请人： Universidad de Almeria , IS Global
- 申请人地址： OTRI-UAL Ctra. de Sacramento s/n Edf. Central 04120 Almería ES
- 专利权人： Universidad de Almeria,IS Global
- 当前专利权人： Universidad de Almeria,IS Global
- 当前专利权人地址： OTRI-UAL Ctra. de Sacramento s/n Edf. Central 04120 Almería ES
- 代理机构： Juncosa Miró, Jaime
- 主分类号： C07F1/12
- IPC分类号： C07F1/12 ; A61K33/24 ; A61P31/04
摘要：
A gold(III) complex, a conjugate of the gold(III) complex, a pharmaceutical composition comprising the gold(III) complex and uses and a process for preparing the gold(III) complex. The complex comprises a group of (S^C)-cyclometallated gold(III) complexes containing a 1,1-dithio ligand, which exhibit antibacterial activity against multiresistant microorganisms or against biofilm activity or biofilm disruption. The gold(III) complex has efficacy against a variety of microorganisms and low toxicity.
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