- 专利标题： NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
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申请号： EP19181338.5申请日： 2014-01-17
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公开(公告)号： EP3567031A1公开(公告)日： 2019-11-13
- 发明人: KALISH, Vincent Jacob , BROOKFIELD, Frederick Arthur , COURTNEY, Stephen Martin , FROST, Lisa Marie , TOSCANO, John, P.
- 申请人： Cardioxyl Pharmaceuticals, Inc.
- 申请人地址： 1450 Raleigh Rd., Suite 212 Chapel Hill, NC 27517 US
- 专利权人： Cardioxyl Pharmaceuticals, Inc.
- 当前专利权人： Cardioxyl Pharmaceuticals, Inc.
- 当前专利权人地址： 1450 Raleigh Rd., Suite 212 Chapel Hill, NC 27517 US
- 代理机构： J A Kemp LLP
- 优先权： US201361754237P 20130118; US201361782781P 20130314
- 主分类号： C07D307/64
- IPC分类号： C07D307/64 ; C07C317/14 ; A61K31/341 ; A61K31/18 ; A61P9/04
摘要：
The disclosed subject matter provides N -substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
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