- 专利标题： 1,3,5-TRIAZINE DERIVATIVE SALT, CRYSTAL, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
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申请号： EP18742199.5申请日： 2018-01-22
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公开(公告)号： EP3572409A1公开(公告)日： 2019-11-27
- 发明人: HUANG, Ticong , XIAO, Huifeng , ZHAO, Rui , LIU, fei , WEI, Wei , XU, Hongjiang , WANG, Xiaojin , WU, Jingli
- 申请人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd. , Lianyungang Runzhong Pharmaceutical Co., Ltd. , Centaurus BioPharma Co., Ltd.
- 申请人地址： No. 369 Yuzhou South Road Haizhou District Lianyungang, Jiangsu 222062 CN
- 专利权人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd.,Lianyungang Runzhong Pharmaceutical Co., Ltd.,Centaurus BioPharma Co., Ltd.
- 当前专利权人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd.,Lianyungang Runzhong Pharmaceutical Co., Ltd.,Centaurus BioPharma Co., Ltd.
- 当前专利权人地址： No. 369 Yuzhou South Road Haizhou District Lianyungang, Jiangsu 222062 CN
- 代理机构： Mewburn Ellis LLP
- 优先权： CN201710047243 20170122; CN201710570764 20170713
- 国际公布： WO2018133856 20180726
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K31/5377 ; A61P35/00
摘要：
The invention discloses a crystal of 4-(tert-butoxyamino)-6-(6-(trifluoromethyl)pyridin-2-yl) -N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine compound, a mesylate salt and crystal thereof, a preparation method thereof, a composition containing thereof, and a use thereof for inhibiting activity of mutant IDH2 and treating cancer.
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