- 专利标题: COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD274/PD-L1 GENE
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申请号: EP19170089.7申请日: 2011-04-06
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公开(公告)号: EP3578657A1公开(公告)日: 2019-12-11
- 发明人: De Fougerolles, Antonin , Novobrantseva, Tatiana , Bettencourt, Brian
- 申请人: Alnylam Pharmaceuticals, Inc.
- 申请人地址: 300 Third Street, 3rd Floor Cambridge, MA 02142 US
- 专利权人: Alnylam Pharmaceuticals, Inc.
- 当前专利权人: Alnylam Pharmaceuticals, Inc.
- 当前专利权人地址: 300 Third Street, 3rd Floor Cambridge, MA 02142 US
- 代理机构: Hoffmann Eitle
- 优先权: US32126310P 20100406
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K31/713 ; A61P31/20
摘要:
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the CD274/PD-L1 gene, and methods of using such dsRNA compositions to inhibit expression of CD274/PD-L1.
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