发明公开
- 专利标题: NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS, SUCH AS LUNG CANCER INCLUDING NSCLC
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申请号: EP19202056.8申请日: 2014-08-04
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公开(公告)号: EP3616711A1公开(公告)日: 2020-03-04
- 发明人: WEINSCHENK, Toni , WALTER, Steffen , FRITSCHE, Jens , SONG, Colette , SINGH, Harpreet
- 申请人: Immatics Biotechnologies GmbH
- 申请人地址: Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 专利权人: Immatics Biotechnologies GmbH
- 当前专利权人: Immatics Biotechnologies GmbH
- 当前专利权人地址: Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 代理机构: Krauss, Jan
- 优先权: GB201313987 20130805; US201361862213P 20130805; GB201403297 20140225
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; A61K39/00 ; C07K7/06 ; C12N5/0783
摘要:
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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