- 专利标题： FUSION PROTEIN CONTAINING TGF- RECEPTOR AND MEDICINAL USES THEREOF
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申请号： EP18798641.9申请日： 2018-05-11
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公开(公告)号： EP3623389A1公开(公告)日： 2020-03-18
- 发明人: GU, Jinming , LUO, Xiao , TAO, Weikang
- 申请人： Jiangsu Hengrui Medicine Co., Ltd. , Shanghai Hengrui Pharmaceutical Co., Ltd.
- 申请人地址： No. 7 Kunlunshan Road Economic and Technological Development Zone Lianyungang Jiangsu 222047 CN
- 专利权人： Jiangsu Hengrui Medicine Co., Ltd.,Shanghai Hengrui Pharmaceutical Co., Ltd.
- 当前专利权人： Jiangsu Hengrui Medicine Co., Ltd.,Shanghai Hengrui Pharmaceutical Co., Ltd.
- 当前专利权人地址： No. 7 Kunlunshan Road Economic and Technological Development Zone Lianyungang Jiangsu 222047 CN
- 代理机构： Potter Clarkson
- 优先权： CN201710334292 20170512
- 国际公布： WO2018205985 20181115
- 主分类号： C07K19/00
- IPC分类号： C07K19/00 ; C07K14/71 ; C07K14/495 ; A61K38/17 ; A61P35/00
摘要：
The present invention provides a fusion protein containing TGF-β receptor and pharmaceutical use thereof. Further, the present invention provides a bifunctional fusion protein comprising the PD-L1 antibody targeting portion and the TGF-βRII extracellular domain, and a pharmaceutical composition comprising the fusion protein containing TGF-β receptor, and the use thereof in the preparation of anti-cancer drug.
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