- 专利标题： HEXAHYDROPYRAZINOBENZ- OR -PYRIDO-OXAZEPINES CARRYING AN OXYGEN-CONTAINING SUBSTITUENT AND USE THEREOF IN THE TREATMENT OF 5-HT2C-DEPENDENT DISORDERS
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申请号： EP19212082.2申请日： 2016-11-24
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公开(公告)号： EP3636651A1公开(公告)日： 2020-04-15
- 发明人: BACKFISCH, Gisela , BAKKER, Margaretha Henrica Maria , BLAICH, Günter , BRAJE, Wilfried , DRESCHER, Karla , ERHARD, Thomas , HAUPT, Andreas , HOFT, Carolin , LAKICS, Viktor , MACK, Helmut , OELLIEN, Frank , PETER, Raimund , RELO, Ana Lucia
- 申请人： AbbVie Deutschland GmbH & Co. KG
- 申请人地址： Mainzer Strasse 81 65189 Wiesbaden DE
- 专利权人： AbbVie Deutschland GmbH & Co. KG
- 当前专利权人： AbbVie Deutschland GmbH & Co. KG
- 当前专利权人地址： Mainzer Strasse 81 65189 Wiesbaden DE
- 代理机构： Bensiek, Stephan
- 优先权： US201562259776P 20151125
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; C07D498/14 ; A61K31/553 ; A61P25/24
摘要：
The present invention relates to compound of formula (I)
wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT 2C receptor, to their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT 2C receptor, and to methods for preventing or treating conditions and disorders which respond to the modulation of 5-HT 2C receptor.
wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT 2C receptor, to their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT 2C receptor, and to methods for preventing or treating conditions and disorders which respond to the modulation of 5-HT 2C receptor.
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