- 专利标题： VACCINE PREPARED UTILIZING HUMAN PARAINFLUENZA VIRUS TYPE 2 VECTOR
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申请号： EP19196282.8申请日： 2013-12-25
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公开(公告)号： EP3636755A1公开(公告)日： 2020-04-15
- 发明人: FUKUMURA, Masayuki , OHTSUKA, Junpei , NOSAKA, Tetsuya , TSURUDOME, Masato , KAWANO, Mitsuo , HARA, Ken-ichiro
- 申请人： BioComo Inc. , Mie University
- 申请人地址： 1325 Komono Komono-cho Mie-gun, Mie 510-1233 JP
- 专利权人： BioComo Inc.,Mie University
- 当前专利权人： BioComo Inc.,Mie University
- 当前专利权人地址： 1325 Komono Komono-cho Mie-gun, Mie 510-1233 JP
- 代理机构： Schwarz & Partner Patentanwälte OG
- 优先权： JP2012283421 20121226
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K39/145 ; A61P31/16 ; C12N7/02 ; C12N7/04 ; A61K48/00 ; A61P35/00 ; A61K39/155 ; A61P31/14
摘要：
Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.
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