- 专利标题： NON-HUMAN ANIMALS EXPRESSING HUMANIZED CD3 COMPLEX
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申请号： EP20160251.3申请日： 2015-11-23
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公开(公告)号： EP3689140A1公开(公告)日： 2020-08-05
- 发明人: OLSON, Kara L. , SMITH, Eric , LAI, Ka-Man Venus , MURPHY, Andrew J. , THURSTON, Gavin , GUO, Dayong
- 申请人： Regeneron Pharmaceuticals, Inc.
- 申请人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 代理机构： Mewburn Ellis LLP
- 优先权： US201462083653P 20141124; US201562106999P 20150123
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; C07K14/725 ; G01N33/50
摘要：
Non-human animals, expressing humanized CD3 proteins are provided. Non-human animals, e.g., rodents, genetically modified to comprise in their genome humanized CD3 proteins are also provided. Additionally, provided are methods and compositions of making such non-human animals, as well as methods of using said non-human animals.
公开/授权文献
- EP3689140B1 NON-HUMAN ANIMALS EXPRESSING HUMANIZED CD3 COMPLEX 公开/授权日：2022-05-11
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