- 专利标题： MULTISPECIFIC ANTIGEN-BINDING MOLECULE HAVING BLOOD COAGULATION FACTOR VIII (FVIII) COFACTOR FUNCTION-SUBSTITUTING ACTIVITY, AND PHARMACEUTICAL FORMULATION CONTAINING SAID MOLECULE AS ACTIVE INGREDIENT
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申请号： EP18860741.0申请日： 2018-09-27
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公开(公告)号： EP3690050A1公开(公告)日： 2020-08-05
- 发明人: TERANISHI, Yuri , KATO, Kazuki , KOGA, Hikaru , IGAWA, Tomoyuki , YAMAGUCHI, Kazuki , SOEDA, Tetsuhiro
- 申请人： Chugai Seiyaku Kabushiki Kaisha
- 申请人地址： 5-1, Ukima 5-chome Kita-ku Tokyo 115-8543 JP
- 专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人地址： 5-1, Ukima 5-chome Kita-ku Tokyo 115-8543 JP
- 代理机构： Vossius & Partner Patentanwälte Rechtsanwälte mbB
- 优先权： JP2017189647 20170929
- 国际公布： WO2019065795 20190404
- 主分类号： C12N15/13
- IPC分类号： C12N15/13 ; A61K39/395 ; A61P7/04 ; C07K16/36 ; C07K16/46 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12P21/08
摘要：
Bispecific antibodies whose FIX activation-inhibiting activity is not elevated and whose FVIII cofactor function-substituting activity is elevated have been successfully discovered.
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